Amanda Q. X. Nio
My research focuses on cardiovascular physiology — with an emphasis on applying and developing non-invasive methods to gain insights into sex differences, ageing, and adaptations to exercise training.
As a graduate student, I examined sex differences in cardiac
function, as well as the impact of the menstrual cycle and menopause
on the female heart. I am particularly interested in the functional
capacity of the heart; how the heart copes with / responds to
physiological stress. To that end, I have successfully assessed
I have strong inter-disciplinary interests and have worked with computer scientists and engineers to test the linear relationship between subharmonic emissions from microbubbles (using ultrasound imaging) and ambient pressure. The successful translation of this idea will equip clinicians and scientists with a technique to measure pressure in the left ventricle non-invasively.
- November, 2014 – present:
- Research Assistant in the Cardiac Modelling and Imaging Biomarkers Group , Department of Biomedical Engineering at King's College London, UK
- 2017 (expected):
- PhD in Cardiovascular Exercise Physiology at Cardiff Metropolitan University , UK
- March – September, 2016:
- Visiting research scholar in the Department of Radiology at Thomas Jefferson University, Philadelphia, PA, USA
- October – November, 2011:
- Temporary staff at the DSO National Laboratories (Combat Protection and Performance 1), Singapore
- MSc (Distinction) in Sports and Exercise Science at the University of Wales Institute, Cardiff, UK (now Cardiff Metropolitan University )
- April, 2007 – September, 2010:
- Member of Technical staff at the DSO National Laboratories (Military Physiology Laboratory, Combat Protection and Performance Programme), Singapore
- BSc (Hons) in Chemistry (minor in Business) at the National University of Singapore , Singapore
Publications & Conference Proceedings
I had to transfer the copyright for some of the articles listed below to the publishers of the journals in which they appeared. However, I am allowed to distribute copies to individuals for personal and/or research use. Your click on any of the links below constitutes your request to me for a personal copy of the linked article. A detailed copyright notice appears in the articles. Nature's web debates published an interesting relevant article by Richard M. Stallman titled "Science must `push copyright aside´" .
- Liu, J.-B., Nio, A. Q. X., Esposito, C., Chen, J., Zhang, J., Zhong, X., Liu, R., Wang, J., Dai, Z., Forsberg, F. & Dave, J. K. (2016, September). Characterizing the subharmonic response of four new microbubble formulations compared with three commercially-available ultrasound contrast agents. In Ultrasonics Symposium (IUS), 2016 IEEE International (pp. 1–4). IEEE.
- Nio, A. Q. X., Stöhr, E. J. & Shave, R. (2015). The female human heart at rest and during exercise: A review. European Journal of Sport Science, 15, 289–295.
- Sudsa-ard, K., Kijboonchoo, K., Chavasit, V., Chaunchaiyakul, R., Nio, A. Q. X., & Lee, J. K. W. (2014). Lactose-free milk prolonged endurance capacity in lactose intolerant Asian males. Journal of the International Society of Sports Nutrition, 11, 49.
- Stembridge, M., Ainslie, P. M., Hughes, M. G., Stöhr, E. J. Cotter, J. D., Nio, A. Q. X. , & Shave, R. (2014). Ventricular structure, function, and mechanics at high altitude: Chronic remodeling in Sherpa vs. short-term lowlander adaptation. Journal of Applied Physiology, 117 334–343.
- Lee, J. K. W., Koh, A. C. H., Koh, S. X. T., Liu G. J. X., Nio, A. Q. X., & Fan P. W. P. (2014). Neck cooling and cognitive performance following exercise-induced hyperthermia. European Journal of Applied Physiology, 114 375–384.
- Lee, J. K. W., Yeo, Z. W., Nio A. Q. X., Koh, A. C., Teo, Y. S., Goh, L. F., Tan, P. M., & Byrne, C. (2013). Cold drink attenuates heat strain during work-rest cycles. International Journal of Sports Medicine, 34, 1037–1042.
- Yeo, Z. W., Fan, P. W. P., Nio, A. Q. X., Byrne, C. , & Lee, J. K. W. (2012). Ice slurry on outdoor running performance in heat. International Journal of Sports Medicine, 33, 859–866.
- Lee, J. K. W., Nio, A. Q. X., Fun, D. C. Y., Teo, Y. S., Chia, E. V., & Lim, C. L. (2012). Effects of heat acclimatisation on work tolerance and thermoregulation in trained tropical natives. Journal of Thermal Biology, 37 366–373.
- Lee, J. K. W., Nio, A. Q. X., Ang, W. H., Johnson, C., Aziz, A. R., Lim, C. L., & Hew-Butler, T. (2011). First reported cases of exercise-associated hyponatremia in Asia. International Journal of Sports Medicine, 32 297–302.
- Lee, J. K. W., Nio, A. Q. X., Ang, W. H., Law, L. Y. L., & Lim, C. L. (2011). Effects of ingesting a sports drink during exercise and recovery on subsequent endurance capacity. European Journal of Sport Science, 11 77–86.
- Lee, J. K. W., Nio, A. Q. X., Lim, C. L., Teo, E. Y. N., & Byrne, C. (2010). Thermoregulation, pacing and fluid balance during mass participation distance running in a warm and humid environment. European Journal of Applied Physiology, 109 887–898.
Selected colleagues and collaborators:
- Pablo Lamata: Lecturer – Sir Henry Dale Fellow at King's College London, UK
- Jason K. W. Lee: Lead Physiologist at DSO National Laboratories, Adjunct Associate Professor at National University of Singapore, and Adjunct Assistant Professor at Nanyang Technological University, Republic of Singapore.
- Flemming Forsberg: Professor of Radiology at Thomas Jefferson University, Philadelphia, PA, USA
- Eric J. Stöhr: Lecturer in Cardiac Physiology and Health at Cardiff Metropolitan University, UK
- Christoph T. Weidemann: Associate Professor at Swansea University, UK